The congestion pressure, clear your head medicine. Clears your head, sinus pressure and shrinks swollen nasal membranes so you can breathe more freely. Vicks Sinex Severe 12 Hour contains an effective decongestant for fast, long lasting relief of nasal stuffiness. From the makers of Vicks. Nothing clears your head faster. Vicks Sinex Severe 12-Hour Decongestant UltraFine Mist Nasal Spray helps relieve the sinus and nasal congestion that often accompanies colds, hay fever, or upper respiratory allergies.