These hemorrhoid suppositories promptly and effectively relieve painful burning, anus itching and discomfort. Using Preparation H Suppositories at night can help you rest comfortably while it reduces internal swelling caused by hemorrhoids. While you can't get rid of hemorrhoids completely, you can relieve symptoms of a flare up with hemorrhoid suppositories from the #1 selling hemorrhoid brand (2), Preparation H. In fact, treating uncomfortable symptoms of hemorrhoids at the first sign can help prevent further irritation.(1) Provoice survey dated from May 2015-August 2017 supports Preparation H is the #1 doctor recommended brand. (2) IRI retail sales data support that Preparation H is the #1 selling hemorrhoid brand in the U.S. (52 weeks ending August 13, 2017). HSA/FSA Eligible. Restrictions apply; contact your insurance provider about plan allowances and requirements. HSA/FSA cards can be accepted in-store but not on Target.com. For Target.com please use a credit card, debit card or gift card to pay for your eligible items and then submit the receipt to your plan based on the current policies for reimbursement.