Imodium Multi-Symptom Relief Caplets are the only over-the-counter brand of anti-diarrheal medicine that combines two powerful medicines to relieve symptoms of diarrhea, as well as gas, cramps, pressure and bloating. Each caplet contains 2 milligrams of loperamide hydrochloride to help relieve diarrhea, and 125 milligrams of simethicone to help other associa..