Stop the itchsanity! Cortizone 10 Maximum Strength Ultra Soothing Anti-Itch Cream works fast to relieve itch and inflammation associated with eczema; psoriasis; poison oak ivy and sumac; and other minor skin irritations. Formulated with maximum-strength hydrocortisone this anti-itch cream contains 10 moisturizers and aloe to soften and soothe skin. Cortizone 10 Ultra Soothing Cream is formulated to be nonirritating and it s fragrance free and dye free. Best of all this itch relief lasts for hours. No wonder it s the No. 1 doctor-recommended anti-itch brand among topical analgesics.* *2021 IQVIA Study.